QS is the shizzle. I started using it instead of Butler after some discussions on this forum few months ago.
By the way, I use both. dont really like QS indexing in the background taking away cpu cycles and gobbling up memory.
revolutionized my computer usage.
-Abracadabra is super useful: use gestures to complete any shortcut/script/function that you normally do w/ QS;
-the comma trick is essential for selecting many files;
-Apple-Esc - selects current object;
-add gcal event;
-email things without opening mail;
-print batch of files without the standard "open, apple-p, enter, close, open, apple-p, enter close, etc etc etc";
-itunes shortcuts for rating songs;
-set a quick reminder to pop up or speak up after a certain period (eg. in 1 hour, remind me with Speak:"Appointment in 10 min")
of course many of the above functions require some fiddling with QS, installing/activating different plugins, and just getting to know QS a bit better; you know, gotta wine it and dine it before it does things for you
Google for tutorials; 43 folders has some useful ones.