I am also curious about what others doing this might say as well. I am impressed with the performance of the Atom, but I do wonder if I would be content with only this (performance-wise).
I tried this with an eeePC 701 when I had one, and it worked for a bit, but I finally decided I wanted more. I now have a quad-core desktop for power use and the Mini for portable use, which is perfect. I'm thinking about at some point adding an eeeBox (or similar) as a low power consumption, always-on file/print server and for light work.
All that to say, I'm curious about others experiences too.